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Response to comment on "The geometric structure of the brain fiber pathways"
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Response to comment on "The geometric structure of the brain fiber pathways"

Van J. Wedeen, Douglas L. Rosene, Ruopeng Wang, Guangping Dai, Farzad Mortazavi, Patric HagmannJon H. Kaas
Science, 卷.337(6102)
09/2012
PMID: 23019633

摘要

Multidisciplinary
In response to Catani et al., we show that corticospinal pathways adhere via sharp turns to two local grid orientations; that our studies have three times the diffusion resolution of those compared; and that the noted technical concerns, including crossing angles, do not challenge the evidence of mathematically specific geometric structure. Thus, the geometric thesis gives the best account of the available evidence.

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