Abstract
New copper(II)-loaded bifunctional phophazenes were developed for the hydrolysis of chemical warfare agents for nerve, such as notorious sarin. Synthesis of these target random copolyphosphazenes containing moieties of glycerol, N,N,N′-trimethyl-N′-(6-hydroxyhexyl)ethylenediamine, and Cu(II) was accomplished in seven steps. p-Nitrophenyl diphenylphosphate as a nerve-agent simulate of sarin was rapidly hydrolyzed by these copolyphosphazene complexes. Their skeleton underwent hydrolysis in aqueous media at 25 °C to yield glycerol, diamine, phosphoric acid, and ammonia. The self-degradability characteristic of the new copolymers is desirable in view of environmental protection.