Abstract
We have successfully demonstrated the diffusion-induced microfabrication of 3D hydrogel structures with desired mechanical heterogeneity for biomedical application. DLP stereolithography with resolution down to 10 µm is employed to fabricate the structures. More specifically, dynamic lithography with varying mask pattern (i.e., intensity distribution) and exposure period are utilized to locally program the photo-polymerization process. As such, 3D hydrogel structures with desired geometries, pore sizes, and mechanical properties can be microfabricated, which could potentially realize the packaging and microenvironment control for tissue engineering.