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A microfluidic device for sorting cancer cells based on cell motility
Conference paper

A microfluidic device for sorting cancer cells based on cell motility

W. Tai, C.F. Yeh, C.C. Wu and C.H. Hsu
15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, Vol.3, pp.1701-1703
2011

Abstract

Cancer cell migration Cell sorting Chemotaxis Metastasis Microfluidics Control and Systems Engineering
In this paper, we present a microfluidic device that allows for sorting of cancer cells based on their chemotactic migration speeds. We used breast cancer cell line cells to demonstrate cell seeding, migration and releasing in our microfluidic device. The ability of our device to provide subpopulations of chemotactically heterogeneous cancer cells should find useful applications in studying cancer and metastasis.

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