Abstract
This study reports a new micro-filter on which the filtration separation mechanism is based on the pneumatically tunable deformation of a PDMS membrane, which blocks the fluid channel with a varied degree defining the remaining passageway to separate the different sized microbeads. Another feature is the incorporation of pneumatic micropumps for automatic liquid handling and the unclogging mechanism using a back-flush operation model. The experimental results showed that the presented device was able to provide highly size-dependent selectivity. © 2009 CBMS.