Abstract
This paper presents an antibiotic biosensors platform for preclinical evaluation of drug release profile of nanocapsules. In this work, carbon nanotubes are used to modify the gold electrode surfaces to enhance the performance of the antibiotic biosensor platform. The results show that antibiotic nanocapsules significantly increase the drug release on the 4th day. And the release rate is 0.0258 μg/ml · hr. The drug release of antibiotic nanocapsules reached 24.98 μg/ml on the 7th day. The antibiotic biosensor platform for preclinical evaluation of drug release profile of nanocapsules presented in this work showed good performance in sensing of antibiotic Teoplanin drug samples.