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An efficient surface modification for selective control of cell attachement using photochemical reaction
Conference paper

An efficient surface modification for selective control of cell attachement using photochemical reaction

Kihoon Jang, Kae Sato, Tomohiro Konno, Kazuhiko Ishihara and Takehiko Kitamori
Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007, pp.1628-1630
2007

Abstract

Adhesion MPC Photochemical PL Chemical Engineering (miscellaneous) Bioengineering
In this paper, we employed photochemical reaction for controlling the cell adhesion on the glass surface. The strategy is based on combining 2-Methacryloyloxyethyl phosphorylcholine (MPC) which is known to reduce non-specific binding, and photolabile linker (PL) for selective cell patterning. The MPC modified surface was irradiated through the MASK by UV and MPC were removed. After selective MPC cleavage, the cells only attached on UV illuminated region, which showed the selective surface control of cell attachment was performed using photochemical reaction.

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