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An integrated lobule-mimetic liver chip for testing hepatotoxicity
Conference paper

An integrated lobule-mimetic liver chip for testing hepatotoxicity

Y.J. Chu, T.H. Punde, S.M. Yang, V.P. Srinivasu, S. Shilpa, R.J. Chen and C.H. Liu
2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11, pp.218-221
2011

Abstract

Cell patterning Dielectrophoresis Gradient Hepatotoxicity
The current trend in personalized healthcare shows that medical care is becoming as individualized as possible. The goal is not only to provide customized diagnostic tests but also to target medicines and dosages more precisely and safely to each patient. Here in this article we report an integrated drug testing device based on lobule-mimetic liver pattern for testing in vitro drug toxicity. We aimed at achieving customized diagnostic tests by reconstructing and mimicking a liver pattern in vitro for predicting the in vivo drug hepatotoxicity. © 2011 IEEE.

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