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Assembly of single cells array using image dielectrophoresis
Conference paper

Assembly of single cells array using image dielectrophoresis

Y.S. Lu, Y.L. Liang, Y.P. Huang, J.Y. Huang, C. Lee and J.Andrew Yeh
TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems, pp.473-476
2007

Abstract

Cell arraying DEP Image dielectrophoresis Single cells array
Cell arraying with single cell per trap is demonstrated using image dielectrophoresis(DEP) and leads to a 5 by 5 single cells array. The tunable energy wells, which were induced by established patterns and image control, were used to confine NIH/3T3 cells. Image was used to help cells overcome the energy barriers. It allows the controllability to rearrange cells, including locally dislodging the excess cells and repositioning them in non-occupant traps. The viability of post-assembled cells that were identified by fluorescence staining of FDA is about 90%. The continuous temperature monitoring shows that the device used reached its thermal equilibrium of 36°C, close to the 3T3 culture temperature of 377deg;C. ©2007 IEEE.

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