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Automatic optimization of drug cocktail on an integated microfluidic system
Conference paper

Automatic optimization of drug cocktail on an integated microfluidic system

W.Y. Huang, C.A. Liu, R.S. Fan, Z.D. Lin, K. Wang and G.B. Lee
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, pp.649-650
2016

Abstract

Automatic integrated system Drug cocktail Drug screening Microfluidic devices Control and Systems Engineering
Drug cocktails have been popular for a variety of therapies of complicated diseases. Nevertheless, it is a tediously challenging task to optimize formulations, especially using traditional methods. Herein, a new integrated microfluidic system was demonstrated to dispense and mix a small amount of drug combination automatically. Based on the preliminary results on cell-level tests, it demonstrates low manual bias of drug formulations. It is envisioned that this automatic system could provide precise and high-throughput drug cocktail formulations and expedite the tedious drug screening process.

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