Abstract
Acoustic droplet vaporization (ADV) is a process when a droplet is converted into a gaseous bubble under ultrasound (US) stimulation. Our previous study has shown that the mechanical force generated by ADV can release drugs and disrupt vessels. It would result in the streaming intact droplets leaking into tissue. In addition, the intact droplets may occur ADV process by subsequent US stimulation. Therefore, this study explored the bioeffects between ADV-Bs and cells within tissue.