Abstract
We propose a 10 nm-scale optical illumination method which enables spectroscopic measurements at 10 nm-scale localized region in closed nanochannels for the first time. Analytes in nanochannels were illuminated by 10-nm-scale near-field light, which is generated by nanoslit apertures on a thin metallic film integrated in the microchip. Transmitted light is also collected with the same nanoslit. The size of detection area was evaluated and found to be 10 nm-scale. This method will contribute to various researches in 10 -10 nm fluidic systems by revealing the nanoscale distribution of flow and liquid property.