Development of a NMR measurement chip for in-site monitoring of chemical synthesis

Yutaka Takahashi; Ryo Sakai; Masamichi Nakakoshi; Satoshi Sakurai; Ryoji Tanaka; Hiroto Suematsu; Hiroaki Utsumi; Takehiko Kitamori

Conference paper

Development of a NMR measurement chip for in-site monitoring of chemical synthesis

Yutaka Takahashi, Ryo Sakai, Masamichi Nakakoshi, Satoshi Sakurai, Ryoji Tanaka, Hiroto Suematsu, Hiroaki Utsumi and Takehiko Kitamori

Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp.879-881

2006

Appears in keyword about Chemistry

Abstract

Chemical synthesis

Interface

Intermediates

Micro device

NMR

Chemical Engineering (miscellaneous)

Bioengineering

Development of a micro device for NMR and its application for in-site monitoring of chemical synthesis were described. Since this device can be inserted into a 5 mm φ NMR sample tube, it is possible to carry out an in-site monitoring of chemical synthesis using a microchip combined with a standard NMR instrument. The performance was demonstrated the direct detection of the intermediates of Grignard reaction. © 2006 Society for Chemistry and Micro-Nano Systems.

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Title: Development of a NMR measurement chip for in-site monitoring of chemical synthesis
Translated title: Development of a NMR measurement chip for in-site monitoring of chemical synthesis
Creators - without role: Yutaka Takahashi - Analytical Instrument Division, JEOL Ltd.
Ryo Sakai - Functional Chemicals R and D Laboratories, Nippon Kayaku Co., Ltd.
Masamichi Nakakoshi - Yokohama National University
Satoshi Sakurai - Analytical Instrument Division, JEOL Ltd.
Ryoji Tanaka - Analytical Instrument Division, JEOL Ltd.
Hiroto Suematsu - Analytical Instrument Division, JEOL Ltd.
Hiroaki Utsumi - Analytical Instrument Division, JEOL Ltd.
Takehiko Kitamori - Department of Applied Chemistry, University of Tokyo
Identifiers: 9957777002106774
Academic Unit: Institute of NanoEngineering and Microsystems, College of Engineering, National Tsing Hua University
Language: English
Resource Type: Conference paper
Publication Details: Micro Total Analysis Systems - Proceedings of MicroTAS 2006 Conference: 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp.879-881

Development of a NMR measurement chip for in-site monitoring of chemical synthesis

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