Development of high yield plasma separation device from whole blood preventing blood cell clogging in a micro/extended-nano chip

We fabricated the device for high yield plasma separation without clogging of blood cells. To control plasma flow after filtering blood cells, dense blood cell flow, and support flow for dilution of dense blood cells, a filter using size-regulated and closely packed extended-nano channels (10-1000 nm) on a micro wall and a capillary which worked as drain and back-pressure regulator were successfully integrated in the device. This device will be useful for blood analysis using a micro/extended-nano chip.