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Development of nanostructures for cell adhesion surface and biological analyses of human cells cultured on the surface
Conference paper

Development of nanostructures for cell adhesion surface and biological analyses of human cells cultured on the surface

Yasuyuki Sakamoto, Kiichi Sato, Takehiko Tsukahara, Takehiko Kitamori, Ichiro Matsumoto, Keiko Abe and Etsuro Yoshimura
Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007, pp.718-720
2007

Abstract

Cell adhesion Cell motility Gene expression Nanostructure Chemical Engineering (miscellaneous) Bioengineering
We studied the interaction between cells and their adhesion surface structure. In this study, we fabricated substrates with/without well-defined nanostripes, on which we cultured human cells and compared morphology, motility and gene expression of the cells by time-lapse imaging and DNA microarray analyses. As a result, it was found that morphology, motility and gene expression of the cells differ evidently between the two conditions.

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