Abstract
We developed a method to measure μg/s order flow rate driven by MPa order pressure in extended nanospace (10 -10 m). Highly pressurized mass flow rate was measured by an electric balance of 1 μg resolution. The obtained flow rate in 500 nm extended nanochannel showed lower value than predicted, which suggests specific fluid dynamics affected by structured water near channel surface and electric double layer in extended nanospace. This study is important to reveal basic science in the space and establish fundamental technology of extended nanofluidic systems for chemical analysis. Copyright © (2011) by the Chemical and Biological Microsystems Society.