Development of on-line desalting device by membrane integration into nanofluidic device

We developed on-line desalting device which realized 31 times decrease of salt concentration. Fabrication and bonding method for membrane integrated micro-nanofluidic device was developed, and high efficient desalting was achieved using the ultra-fast diffusion in micro-nanospaces. From the results, increase of sensitivity of MS is expected, and this device using micro-nanofluidics will greatly contribute to separation analysis.