Direct detection of low concentration DNA in high ionic strength solution with AlGaN/GaN high electron mobility transistors

Yen-Wen Chen; Yu-Lin Wang

doi:10.1149/07540.0021ecst

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Conference paper

Direct detection of low concentration DNA in high ionic strength solution with AlGaN/GaN high electron mobility transistors

Yen-Wen Chen and Yu-Lin Wang

ECS Transactions, Vol.75(40), pp.21-24

2016

DOI: https://doi.org/10.1149/07540.0021ecst

Abstract

DNA

HEMT

Engineering (all)

In this research, the direct detection of DNA sequences in physiological salt concentration by FET based biosensor has been investigated. FET having high transconductance gain, can significantly improve the S/N ratio and sensitivity. As the complementary DNA concentration, ranging from lfM to lOOfM, is introduced, the current gain of the device changes accordingly. The sensor can efficiently detect target DNA down to a low concentration of 1 fM.

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Title: Direct detection of low concentration DNA in high ionic strength solution with AlGaN/GaN high electron mobility transistors
Translated title: Direct detection of low concentration DNA in high ionic strength solution with AlGaN/GaN high electron mobility transistors
Creators - without role: Yen-Wen Chen - National Tsing Hua University
Yu-Lin Wang - National Tsing Hua University , Institute of NanoEngineering and MicroSystems
Publication Details: ECS Transactions, Vol.75(40), pp.21-24
Identifiers: 9781607685395; 9957771432606774
Academic Unit: Institute of NanoEngineering and Microsystems, College of Engineering, National Tsing Hua University
Language: English
Resource Type: Conference paper

Direct detection of low concentration DNA in high ionic strength solution with AlGaN/GaN high electron mobility transistors

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