Logo image
Electrochemical detection of the neurotransmitter dopamine by nanoimprinted sub-μm microelectrodes and CMOS circuitry with near 100% collection efficiency
Conference paper   Open access   Peer reviewed

Electrochemical detection of the neurotransmitter dopamine by nanoimprinted sub-μm microelectrodes and CMOS circuitry with near 100% collection efficiency

Chang-Wen Huang and Michael S.-C. Lu
Procedia Engineering, Vol.5, pp.1196-1199
2010

Abstract

Capacitive CMOS Transducer Ultrasound
The sub-μm interdigitated microelectrodes presented in this work aims at achieving a high collection efficiency for electrochemical dopamine (DA) detection. Through nanoimprint technology, sub-μm microelectrodes can be batch fabricated without relying on the expensive electron-beam lithography repeatedly. The applied reduction and oxidation potentials are determined by cyclic voltammetry at -0.2 V and 0.6 V. The effectiveness of nanoimprinted electrodes is clearly illustrated by the small deviations of produced electrochemical currents with respect to analytic values. The sensitivities are 2.89 and 1.73 nA/μM for interdigitated microelectrodes with gaps of 300 and 600 nm. The average collection efficacy values are 97.9% and 95.4%, respectively. Signal transduction is achieved by a CMOS sensing circuit. The detectable resolution is about 0.1 μM.
url
https://doi.org/10.1016/j.proeng.2010.09.326View
Published (Version of record) Open

Related links

Metrics

1 Record Views

Details

Logo image