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Enhancement of E6 protein binding on binding-orientation-sensitive mixed SAMs molecules
Conference paper

Enhancement of E6 protein binding on binding-orientation-sensitive mixed SAMs molecules

F.G. Tseng, J.K. Hwang, S.W. Hung, J.M. Chang, T.W. Huang, Y.T. Tseng, K.M. Huang and C.C. Chieng
2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 Technical Proceedings, pp.442-445
2005

Abstract

Atomic force microcopy Binding force Mixed SAMs Molecular Dynamic simulstions Protein molecules
This study proposed the use of mixed SAMs of different chain lengths to bind the E6 protein molecules. Atomic Force Microscopy measurement and molecular dynamic simulation are performed to demonstrate the successful enhancement of the binding of E6 protein with mixed SAMs of proper mixing ratio of thiols (C9 and C5) and the determination of binding orientations.

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