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Enhancing Accessibility and Reproducibility of Flow Cytometry Data Analysis with Panel-Agnostic Machine Learning-Based Automated Cross-Panel Sample-Level Classification for Acute Leukemia
Conference paper

Enhancing Accessibility and Reproducibility of Flow Cytometry Data Analysis with Panel-Agnostic Machine Learning-Based Automated Cross-Panel Sample-Level Classification for Acute Leukemia

En-Ping Chu, Yu-Fen Wang, Tsung-Chih Chen, 祈均 李, Joseph Hanson, Joseph D. Tario, Kai-Fu, Sara A Monaghan, Paul Wallace and Bor-Sheng Ko
International Clinical Cytometry Society (ICCS)
2024

Abstract

Flow Cytometry;Machine Learning;Acute Leukemia
  • The lack of standardization in panel design and the complexity of manual analysis for flow cytometry (FC) data have hindered the speed and the spread of both implementation and the service capacity of flow cytometry being in the emerging countries.
  • This study employs multiple machine learning (ML) approaches to develop an automated panel-agnostic AML classification at both sample and cell levels from several distinct flow cytometry laboratories.

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