FEMTOLITER VOLUMETRY BY LAPLACE VALVE AND MECHANICAL VALVE FOR SAMPLE INJECTION IN FEMTOLITER CHROMATOGRAPHY

Kyojiro Morikawa; Shin-Ichi Murata; Hiroki Sano; Yutaka Kazoe; Takehiko Kitamori

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FEMTOLITER VOLUMETRY BY LAPLACE VALVE AND MECHANICAL VALVE FOR SAMPLE INJECTION IN FEMTOLITER CHROMATOGRAPHY

Kyojiro Morikawa, Shin-Ichi Murata, Hiroki Sano, Yutaka Kazoe and Takehiko Kitamori

MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp.879-880

2022

Appears in keyword about Chemistry

Abstract

Fluid Control

Liquid Chromatography

Nanofluidics

Valve

Chemical Engineering (miscellaneous)

Bioengineering

Chemistry (all)

Control and Systems Engineering

We developed separation device with reproducible injection by integration of Laplace valve and mechanical nano-valve. The injected sample volume was only 940 fL, and the CV of the volume was 3.1%, which showed enough performance for quantitative analysis. In addition, proteins were successfully separated with 2.3×10 ⁴ plate. This device will greatly contribute to nice application in separation science and biology like single cell proteomics.

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Title: FEMTOLITER VOLUMETRY BY LAPLACE VALVE AND MECHANICAL VALVE FOR SAMPLE INJECTION IN FEMTOLITER CHROMATOGRAPHY
Translated title: FEMTOLITER VOLUMETRY BY LAPLACE VALVE AND MECHANICAL VALVE FOR SAMPLE INJECTION IN FEMTOLITER CHROMATOGRAPHY
Creators - without role: Kyojiro Morikawa - National Tsing Hua University
Shin-Ichi Murata - The University of Tokyo
Hiroki Sano - The University of Tokyo
Yutaka Kazoe - Keio University
Takehiko Kitamori - National Tsing Hua University
Publication Details: MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp.879-880
Identifiers: 9781733419048; 9957768864306774
Academic Unit: Institute of NanoEngineering and Microsystems, College of Engineering, National Tsing Hua University; Department of Power Mechanical Engineering, College of Engineering, National Tsing Hua University
Language: English
Resource Type: Conference paper

FEMTOLITER VOLUMETRY BY LAPLACE VALVE AND MECHANICAL VALVE FOR SAMPLE INJECTION IN FEMTOLITER CHROMATOGRAPHY

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