Abstract
We have fabricated a culture and bioassay system using human arterial endothelial cells (HAECs) in a thermally fused-glass microchip which is chemically stable and favorable for optical detections. HAECs reached confluence within 4 days and responded to inflammatory cytokine, tumor necrosis facor-Į (TNF-Į) and attached to more leukocyte cell line, HL-60 cells than unstimulated HAECs.