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Glass microchip-based bioassay system using human arterial endothelial cells
Conference paper

Glass microchip-based bioassay system using human arterial endothelial cells

Yo Tanaka, Yuji Kikukawa, Kae Sato, Yasuhiko Sugii and Takehiko Kitamori
Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007, pp.137-139
2007

Abstract

Endothelial cell Glass microchip Leukocyte Vascular model Chemical Engineering (miscellaneous) Bioengineering
We have fabricated a culture and bioassay system using human arterial endothelial cells (HAECs) in a thermally fused-glass microchip which is chemically stable and favorable for optical detections. HAECs reached confluence within 4 days and responded to inflammatory cytokine, tumor necrosis facor-Į (TNF-Į) and attached to more leukocyte cell line, HL-60 cells than unstimulated HAECs.

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