High yield cell fusion chip via hydrodynamic approach and 3D liquid metal electrodes

Hung-Po Chen; Kuo-Wei Chang; Shih-Mo Yang; Jen-Pin Chen; Ciou-Wen Lin; Shilpa Sivashankar; Srinivasu Valagerahally Puttaswamy; Yen-Ta Lu; Cheng-Hsien Liu

Conference paper

High yield cell fusion chip via hydrodynamic approach and 3D liquid metal electrodes

Hung-Po Chen, Kuo-Wei Chang, Shih-Mo Yang, Jen-Pin Chen, Ciou-Wen Lin, Shilpa Sivashankar, Srinivasu Valagerahally Puttaswamy, Yen-Ta Lu and Cheng-Hsien Liu

Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012, pp.425-427

2012

Appears in keyword about Chemistry

Abstract

3D liquid metal electrodes

3D microfluidic chip

Cell fusion

We report a 3D microfluidic chip for cell fusion which utilizes hydrodynamic force for trapping the cells followed by fusion with the aid of electrokinetic phenomena via 3D liquid metal electrodes. This two layer microchannel design gives high cell fusion yield with higher efficiency without any cell damage.

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Title: High yield cell fusion chip via hydrodynamic approach and 3D liquid metal electrodes
Creators - without role: Hung-Po Chen - Department of Power Mechanical Engineering, National Tsing-Hua University
Kuo-Wei Chang - Department of Power Mechanical Engineering, National Tsing-Hua University
Shih-Mo Yang - Department of Electrophysics, National Chiao Tung University
Jen-Pin Chen - Department of Power Mechanical Engineering, National Tsing-Hua University
Ciou-Wen Lin - Department of Power Mechanical Engineering, National Tsing-Hua University
Shilpa Sivashankar - Department of Power Mechanical Engineering, National Tsing-Hua University
Srinivasu Valagerahally Puttaswamy - Department of Power Mechanical Engineering, National Tsing-Hua University
Yen-Ta Lu - Mackay Memorial Hospital
Cheng-Hsien Liu - Department of Power Mechanical Engineering, National Tsing-Hua University
Identifiers: 9780979806452; 9957772835506774
Academic Unit: Institute of NanoEngineering and Microsystems, College of Engineering, National Tsing Hua University
Language: English
Resource Type: Conference paper
Publication Details: Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012, pp.425-427

High yield cell fusion chip via hydrodynamic approach and 3D liquid metal electrodes

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