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Integration of glass deformation nanochannel open/close valves into a nanofluidic device and femto-liter fluid operations
Conference paper

Integration of glass deformation nanochannel open/close valves into a nanofluidic device and femto-liter fluid operations

Hiroki Sano, Yutaka Kazoe, Kyojiro Morikawa and Takehiko Kitamori
MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp.370-371
2020

Abstract

Fluid operation;Integration;Nanochannel;Nanofluidics;Open/close;Valve Chemical Engineering (miscellaneous) Bioengineering Chemistry (all) Control and Systems Engineering

We developed a system for controlling multiple nanochannel open/close valves, and developed a method of fluid control for nanofluidics. We previously developed a nanochannel open/close valve utilizing glass deformation and verified fluid operations using the valve. However, because there was no system for controlling multiple valves, stable fluid control has not been realized. With our system, switching of two nanochannel flows within 0.25 s utilizing two valves was demonstrated. The repeatability of the flow switching was as high as ±1.6 %. This new nanofluidic controlling method using valves will realize sophisticated fluid operations and novel nanofluidic analytical devices.

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