Abstract
Free radicals have been demonstrated in related to various human health problems. Among these free radicals, hydroxyl radical is the highest oxidized species. We developed a novel, simple and cheap polyaniline microchip sensor that can detect hydroxyl radical generated from Fenton reaction in real time. The notable current (or conductance) change of sensor was induced when ferrous ion was added, indicating that hydroxyl radical react with polyaniline to cause the current decreased. There are many advantages of polyaniline microchip sensor, including simple fabrication of sensor, easy measurement and portable design. Furthermore, the polyaniline microchip sensor is a potential tool for cancer biomarkers, cholesterol and glucose detection.