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Live circulating tumor cells selection on self-assembled cell array (SACA) chip by in-parallel image analysis and in-situ cell capture
Conference paper

Live circulating tumor cells selection on self-assembled cell array (SACA) chip by in-parallel image analysis and in-situ cell capture

Shin Yao Wu, Hsueh Yao Chu, Yu Chen Cheng, Cheng Hsuan Chu and Fan Gang Tseng
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017, pp.856-857
2020

Abstract

Automatic image system Cell capture Circulating tumor cells Chemical Engineering (miscellaneous) Bioengineering
This study reports the rapid selection of identified live CTCs from whole blood on SACA chip by automatic imaging system and in-situ cell capturing process. It takes about 50 minutes to examine 2 ml whole blood sample. The image resolution of a cell (10 Pm in diameter) can reach about 730 pixels/cell in the photograph, high enough for computers to analyzing fluorescence information automatically. The identified live CTCs can be accurately captured individually by using home-made micro-cell-capture system. All cells are remained highly viable after the entire process.

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