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Low-environmental-interference highly-sensitive TMR biosensor for in-vitro diagnosis application
Conference paper

Low-environmental-interference highly-sensitive TMR biosensor for in-vitro diagnosis application

Yi-Ching Kuo, Hsin-Han Lee, Ding-Yeong Wang, Yao-Jen Chang, Shan-Yi Yang, Yu-Chen Hsin, I-Jung Wang, Guan-Long Chen, Yi-Hui Su, Sk Ziaur Rahaman, …
2020 International Symposium on VLSI Technology, Systems and Applications, VLSI-TSA 2020, pp.56-57
08/2020

Abstract

Artificial Intelligence Hardware and Architecture Electrical and Electronic Engineering Electronic Optical and Magnetic Materials
The Tunnel Magnetoresistance (TMR) biosensor with different magnetic tunnel junction (MTJ) aspect ratios was developed. With the specific designs and the process development, the sensing distance of the active sensor could be shortened to 74.2 nm to obtain larger magnetic bead (MB) induced signal and the reference sensor, whose sensing distance was 350 nm thicker than that of the active sensor, was used as the baseline during the detection to eliminate the environment noise. The simulation method which could well characterize the TMR element was also developed. Finally, the experimental results of the MB detection was shown. W1/L8 MTJ structure, whose resistance was 40 , had the highest sensitivity (0.444 /MB). Overall, according to the various designs of the MTJ structures, the TMR biosensor with low environmental interference and high sensitivity could be used in variety of the in-vitro diagnosis of Point of Care (PoC) applications in future.

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