Abstract
we discuss the development of innovative methods for ecaluating motor activity in patients with Parkinson's disease.Incorporating both biomarkers(heart rate variability, electromyography, inertial sensors) and phenomenological components, this programme is designed for use in the patient's home, during normal daily activities and is, as such, readily transferrable to other ergonomic applications. Our presentation will focus particularly on wireless and multi-sensor technology developed as an integrated system allowing us to collect multi-dimensional data sets. Procedures adapted for such ecological situations will be presented, including robust analysis with regard to impulsive noise and artefacts; analysis of nonstationary signals.