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Multistep mixing, reaction and detection system in an extended-nano fluidic network
Conference paper

Multistep mixing, reaction and detection system in an extended-nano fluidic network

Yo Tanaka, Hong Trang Ngo, Yutaka Kazoe, Hisashi Shimizu, Kazuma Mawatari and Takehiko Kitamori
15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, Vol.1, pp.380-382
2011

Abstract

Continuous flow chemical processing (CFCP) Extended-nano channel Thermal lens microscope (TLM) Control and Systems Engineering
In this report, we developed an extended-nano (10-1000 nm) fluidic network to realize continuous flow chemical processing (CFCP) for single cell secretion analysis. Firstly, equivalent mixing was demonstrated in the network by optimizing fabrication conditions and applied pressure. Secondly, chemical reaction was realized in the network, and the products were detected by differential interference contrast thermal lens microscope (DIC-TLM). This is the smallest reaction channel network, and will be applied for single cell activity analysis. Copyright © (2011) by the Chemical and Biological Microsystems Society.

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