Nanoparticle-amplifled optical interferometer biosensor toward single molecular detection

B.Y. Shew; S.L. Wei; Y.H. Tsail; Y.C. Cheng; C.C. Fu

doi:10.1109/NEMS.2007.352245

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Conference paper

Nanoparticle-amplifled optical interferometer biosensor toward single molecular detection

B.Y. Shew, S.L. Wei, Y.H. Tsail, Y.C. Cheng and C.C. Fu

Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007, pp.127-130

2007

DOI: https://doi.org/10.1109/NEMS.2007.352245

Abstract

Biosensor

Nanoparticle

Planar interferometer

Sensitivity

This paper reports a new method using a NIR Mach-Zehnder interferometer (MZI), plus conjugated gold nanoparticle, to achieve ultra-sensitive biochemical detection. Due to the combination of interferometru: measurement, long interaction length and nanoparticle amplification, the MZI chip can detect the analyte with a equipollent concentrations of 105 molecular/ml or 10-14 g/ml, which is approaching the ultimate goal of single molecular detection. © 2007 IEEE.

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Title: Nanoparticle-amplifled optical interferometer biosensor toward single molecular detection
Creators - without role: B.Y. Shew - National Synchrotron Radiation Research Center
S.L. Wei - National Synchrotron Radiation Research Center
Y.H. Tsail - National Synchrotron Radiation Research Center
Y.C. Cheng - National Tsing Hua University
C.C. Fu - National Tsing Hua University
Publication Details: Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007, pp.127-130
Identifiers: 1424406102; 9781424406104; 9957770061706774
Academic Unit: National Tsing Hua University
Language: English
Resource Type: Conference paper

Nanoparticle-amplifled optical interferometer biosensor toward single molecular detection

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