Abstract
Using nanoparticles as nanoantennas that are engineered to efficiently couple with the resonant modes of a photonic crystal surface, amplification of surface enhanced Raman spectroscopy and resonant enhanced absorption provides high signal-to-noise mechanisms for sensing biomolecular interactions with single-event resolution. This talk will summarize the underlying theory, sensor/instrument design, and applications in sensing viral pathogens, miRNA biomarkers for cancer, and proteins.