Abstract
Here, we report a first example of chemical reaction analyzed by NMR spectroscopy in extended-nano spaces (10-1000 nm scale spaces). To realize on-chip analysis of chemical reaction, a novel NMR chip was designed. We also show that a reaction speed of Diels-Alder reaction of cyclopentadiene was accelerated in extended-nano spaces. Copyright © (2011) by the Chemical and Biological Microsystems Society.