Abstract
In recent years, digital microfluidic (DMF) biochips have become the most popular and emerging technology for implementing a wide range of biochemical laboratory protocols on a small hand-held device. Due to its high-throughput, high-sensitivity, automatic control, and low cost, DMF biochips are now being considered for several real-life applications like on-chip diagnosis of various cardiovascular diseases, cancer, diabetes, HIV/AIDS and others. As the complexity of biochemical assay increases, powerful computer-aided-design tools are needed for developing DMF biochips. This paper presents an overview of recent research trends in the chip-level design of DMF biochips. © 2014 IEEE.