Separation and detection of biomolecules in extended-nano channel using UV differential interference contrast thermal lens microscope

H. Shimizu; N. Miyawaki; A. Smirnova; K. Mawatari; T. Kitamori

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Conference paper

Separation and detection of biomolecules in extended-nano channel using UV differential interference contrast thermal lens microscope

H. Shimizu, N. Miyawaki, A. Smirnova, K. Mawatari and T. Kitamori

20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, pp.1430-1431

2016

Appears in keyword about Chemistry

Abstract

Chromatography

Nanofluidics

Photothermal

Control and Systems Engineering

Reversed-phase chromatography and UV absorbance detection system was miniaturized to femtoliter scale. Three nonlabeled nucleic acids were separated in an open tubular nanofluidic channel modified with C18 and detected by photothermal detection. The volume of the injected sample was only ∼500 fL and the mole number of detected molecule was ∼500 amol.

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Title: Separation and detection of biomolecules in extended-nano channel using UV differential interference contrast thermal lens microscope
Translated title: Separation and detection of biomolecules in extended-nano channel using UV differential interference contrast thermal lens microscope
Creators - without role: H. Shimizu - School of Engineering , University of Tokyo
N. Miyawaki - School of Engineering , University of Tokyo
A. Smirnova - School of Engineering , University of Tokyo
K. Mawatari - School of Engineering , University of Tokyo
T. Kitamori - School of Engineering , University of Tokyo
Publication Details: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, pp.1430-1431
Identifiers: 9780979806490; 9957777120306774
Academic Unit: Institute of NanoEngineering and Microsystems, College of Engineering, National Tsing Hua University
Language: English
Resource Type: Conference paper

Separation and detection of biomolecules in extended-nano channel using UV differential interference contrast thermal lens microscope

Abstract

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