Abstract
A novel on-chip piezoelectric ultrasonic transceiver array has been designed for ultrasensitive detection of doxycycline antibiotic drug. The piezoelectric polymer ultrasonic biosensor contains a transmitter and a receiver, which are made of electrodeposited P(VDF-TrFE), and is integrated with a 60 Hm sticker-based microfluidic channel. This developed biosensor has been characterized for detection of doxycycline, which is frequently used in animals, for different concentrations within 2 minutes, and the limit of detection reaches 50 ppb. In future, the developed sticker microfluidic chips with on-chip piezoelectric polymer ultrasonic transceiver array has the advantages of low cost, ease of fabrication, and highly-sensitive detection.