Synchrotron X-ray synthesized gold nanoparticles for tumor therapy

C.C. Chien; C.H. Wang; T.E. Hua; P.Y. Tseng; T.Y. Yang; Y. Hwu; Y.J. Chen; K.H. Chung; J.H. Je; G. Margaritondo

doi:10.1063/1.2436445

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Conference paper

Synchrotron X-ray synthesized gold nanoparticles for tumor therapy

C.C. Chien, C.H. Wang, T.E. Hua, P.Y. Tseng, T.Y. Yang, Y. Hwu, Y.J. Chen, K.H. Chung, J.H. Je and G. Margaritondo

AIP Conference Proceedings, Vol.879, pp.1908-1911

2007

DOI: https://doi.org/10.1063/1.2436445

Appears in keyword about Physics

Abstract

Gold nanoparticle

Synchrotron x-ray

Tumor therapy

Physics and Astronomy (all)

Highly concentrated gold nanoparticles (20 ± 5 nm) were produced by an x-ray irradiation method. The particles were then examined for the interactions between gold and tumor cells under x-ray radiation conditions. The biological effects of gold nanoparticles were investigated in terms of the internalization, cytotoxicity and capability to enhance x-ray radiotherapy. The results of this investigation indicated that x-ray derived gold nanoparticles were nontoxic to CT-26 cell line and immobilized within cytoplasm. The irradiation experiments provided further evidence that gold nanoparticles were capable of enhancing the efficiency of radiotherapy. © 2007 American Institute of Physics.

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Title: Synchrotron X-ray synthesized gold nanoparticles for tumor therapy
Translated title: Synchrotron X-ray synthesized gold nanoparticles for tumor therapy
Creators - without role: C.C. Chien - Pohang University of Science and Technology
C.H. Wang - Pohang University of Science and Technology
T.E. Hua - Pohang University of Science and Technology
P.Y. Tseng - Institute of Physics, Academia Sinica
T.Y. Yang - Institute of Physics, Academia Sinica
Y. Hwu - Pohang University of Science and Technology
Y.J. Chen - Pohang University of Science and Technology
K.H. Chung - Pohang University of Science and Technology
J.H. Je - Pohang University of Science and Technology
G. Margaritondo - Pohang University of Science and Technology
Publication Details: AIP Conference Proceedings, Vol.879, pp.1908-1911
Identifiers: 0735403732; 9780735403734; 9957771499006774
Academic Unit: Department of Engineering and System Science, College of Nuclear Science, National Tsing Hua University
Language: English
Resource Type: Conference paper

Synchrotron X-ray synthesized gold nanoparticles for tumor therapy

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