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A CMOS 256-Pixel Self-Photovoltaics-Powered Subretinal Prosthetic Chip with Wide Image Dynamic Range and Shared Electrodes and Its in Vitro Experimental Results on Rd1 Mice
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A CMOS 256-Pixel Self-Photovoltaics-Powered Subretinal Prosthetic Chip with Wide Image Dynamic Range and Shared Electrodes and Its in Vitro Experimental Results on Rd1 Mice

C.-Y. Wu, C.-K. Tzeng, S.-Y. Huang, F.-L. Chu, C.-C. Chiao, Y.-C. Tsai, J. Ohta 和 T. Noda
Midwest Symposium on Circuits and Systems, 卷.2019-August, 頁碼.29-32
2019
DOI: https://doi.org/10.1109/MWSCAS.2019.8885223

摘要

CMOS image sensor implantable chip subretinal prostheses Electrodes Electrophysiology Light Mammals Photoelectrochemical cells Photovoltaic cells Pixels Prosthetics Adaptive backgrounds Bi-directional CMOS image sensor Electrical measurement Image dynamic ranges implantable chip Patch clamp experiments Subretinal prosthesis CMOS integrated circuits
A self-photovoltaics-powered CMOS 256-pixel implantable chip with wide image dynamic range and shared electrodes is proposed and fabricated for subretinal prostheses. The infra-red (IR) light is incident only on photovoltaic cells of the chip whereas the visible light is mainly incident on pixels. The proposed adaptive background cancellation circuit (ABCC) is adopted to increase the image dynamic range so that the subretinal chip can adapt for different surrounding illuminances. Moreover, the bi-directional sharing electrodes (BDSEs) is used to increase electrode size under the same chip area and boost the stimulation charges to 11.4 nC. The functions of the chip have been successfully validated with both electrical measurement and in vitro patch clamp experiments with the retinas of Rd1 mice. © 2019 IEEE.

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