摘要
This study reports a new cell delivery and fixing microfluidic system integrating micro-pumps, micro-valves, dielectrophoretic electrodes and micro-coupler devices for on-chip dual-beam optical trap applications. After focusing and delivering cells to the detection area, the cell can be fixed at the top side of a micro flow channel by micro-valves and a negative dielectrophoretic (N-DEP) force for optical trapping and manipulation. The fiber micro-coupler can be used to promote the probability in trapping cells. Results show the proposed system can trap the cell successfully by a dual-beam optical trap. It is promising for applications of a single cell/particle optical trapping, manipulation and analysis. © 2007 CBMS.