摘要
This study presents a new chip-based cell counting and sorting system utilizing several crucial microfluidic devices for biological applications. Recently, micromachine-based flow cytometry has been widely investigated for cell counting/sorting applications. By using a cell sampling and hydrodynamic focusing controller, cell sample driving and hydrodynamic focusing were generated. For the purpose of fluorescence detection, multiple buried optical fibers were then used to transmit the light source and collect emitted fluorescence signals in/out of the chip device. Lastly, a fluidic switching mechanism consisting of three pneumatic micro-valves were used for cell sorting. Copyright © 2005 by the Transducer Research Foundation, Inc.