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AN ARTIFICIAL CILIA BASED MICROMIXER FOR SUPERIOR ZEBRAFISH SPERM ACTIVATION
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AN ARTIFICIAL CILIA BASED MICROMIXER FOR SUPERIOR ZEBRAFISH SPERM ACTIVATION

Chia-Yuan Chen, Pin-Yi HuangBivas Panigrahi
30TH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS 2017), 頁碼.1240-1243
Proceedings IEEE Micro Electro Mechanical Systems
01/01/2017
Web of Science ID: WOS:000402552000318

摘要

Engineering Engineering, Electrical & Electronic Engineering, Mechanical Nanoscience & Nanotechnology Science & Technology Science & Technology - Other Topics Technology
The objective of this study is to propose an artificial cilia based microfluidic device for efficient activation of zebrafish sperm by controlling the hydro-dynamics induced on the zebrafish sperm from the artificial cilia beating. The magnitude of fluid shear which has significant effect on the success of sperm activation was precisely controlled through this proposed device. A superior sperm activation of an absolute value of 70% with an average value of 65% was achieved with a statistical significance (p-value < 0.05). The present design will advance the practice of the sperm activation significantly through the microfluidic platform.

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