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Modification of leaf sequences of dynamic multileaf collimator in radiotherapy: respiratory motion target tracking and total body irradiation
Dissertation

Modification of leaf sequences of dynamic multileaf collimator in radiotherapy: respiratory motion target tracking and total body irradiation

Chen, Ho-Hsing
Doctor of Philosophy (PHD), 國立清華大學, 生醫工程與環境科學系
2012

Abstract

強度調控放射治療 呼吸運動 全身放射治療 動態照野交界 多葉式準值儀 及時動態追蹤 Dynamic multileaf collimator Leaf sequences respiratory motion Dynamic tracking Total body irradiation Dynamic field matching
we applied an aperture adaptive technique with a visual guiding system to tackle the problem of respiratory motion. A homemade computer program showing a cyclic respiratory pattern was projected onto the ceiling to visually help the patient adjust their respiration. Once the respiratory motion became regular, the leaf sequence could be synchronized with the target motion. An oscillator was employed to simulate the patient’s breathing pattern. Two simple fields and one IMRT field were measured to verify the accuracy. Preliminary results showed that after appropriate training, the amplitude and duration of a volunteer’s breathing could be well controlled by the visual guiding system. The high dose gradient at the edges of the radiation fields were successfully retained. The aperture adaptive technique with the visual guiding system can be an inexpensive and feasible alternative without compromising delivery efficiency in clinical practice. this study was to develop a total body irradiation technique that does not require additional devices or sophisticated procedures to overcome the space limitation of a small treatment room by modifying the leaf sequences of intensity modulated fields.The technique treated the patient lying on the floor anteriorly and posteriorly. For each AP/PA treatment, two complementary fields with dynamic field edges were matched over an overlapped region defined by the marks on the body surface.The results confirmed that the technique is capable of delivering a uniform dose distribution to the midline of the body in a small treatment room while keeping the lung dose within the tolerance level.

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