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1,2-胺基醇在催化不對稱二乙基鋅加成反應之研究
Thesis

1,2-胺基醇在催化不對稱二乙基鋅加成反應之研究

吳志龍
Masters, 國立清華大學, 化學系
2004

Abstract

胺基醇 二乙基鋅 催化不對稱反應
The asymmetric addition of diethyl zinc to aldehydes were catalized by the chiral □-amino alcohol 23 derived from ketopinic acid in few stepts. When the addition of Et2Zn to benzaldehyde was conducted at room temperature in the presence of 2 mol % catalyst, 1-phenylpropanol was obtained in 93 % e.e. in 15 minute.

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