Abstract
Due to the rapid growth of 3D protein structures solved in recent years, it becomes increasingly important that we need an efficient, automated tool to search similar local 3D fragments embedded in the 3D conformation of proteins. We designed the method of identification of the LocAl Conformations Of Proteins (LACOP) software to detect similar local sub-structure of proteins. Our result compared favorable software with fragment-search methods. There were two advantages in LACOP: First, it saved much time to scan whole PDB database. Second, it could compare motif structure.