Abstract
The study was divided into four parts described as in thefollowing: Part Ⅰ. The effects of 137Csγ-ray irradiation (RT)on cellular immunocompentence (CI) of mice were investigated inthis part. The dosage of RT, including 5, 50, 100, 200, 300and 400 cGy. The results revealed that all dosage of 100, 200,300 and 400 cGy of RT played an evident inhibitory effects oncounts of leukocyte (Leu) and its differential counts (DC), thespleen weight (SW) and the blastogenic response of splenocytes(BRS) to mitogens, such as PHA, PWM, Con A and LPS in mice.The higher the dosage ofγ-irradiation, the more inhibition ofCI in mice was found. Prat Ⅱ. The effects of Glycyrrizae radix(GL) and Glycyrrhizic acid (GA) on CI in 4 Gy γ-ray irradiatedmice was investigated in this part. The results revealed thatGA and GL were effective in enhancing the recovery of leukocyteand its differential counts, and the BRS to PHA, PWM, Con A andLPS from the inhibition of 4 Gy γ-irradiation. GA and GLcould help the recovery of the CI in the γ-ray irradiatedmice. Part Ⅲ. The effects of GA and GL on promoting therecovery of mice from radiation injury was investigated in thispart. The results revealed that GA and GL had the beneficialeffects to restoration of radiation injury in spleen of mice.Part Ⅳ. The effects of Polyporus (PU) and PSK (Krestin) on CIof 1 Gy γ-ray irradiated mice was investigated in this part.The results revealed that PU and PSK were effective inenhancing the recovery of Leu and DC, and the BRS to mitogensfrom the inhibition of 1 Gy γ-irradiation. PU and PSK couldhelp the recovery of the CI in the γ-ray irradiated mice.