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以三氯化鋁媒介具有丙二烯支鏈之α-碘基酮離子性環化反應研究
Thesis

以三氯化鋁媒介具有丙二烯支鏈之α-碘基酮離子性環化反應研究

陳昭翔
Masters, National Tsing Hua University
2004

Abstract

β-丙二烯支鏈之α-碘基酮離子性環化反應三氯化鋁碘正離子加成反應β-丙二烯支鏈1,4-加成碘化方法α-碘基酮
In this thesis, we study on the ionic iodo carbocyclization of the α-iodocycloalkanones bearing a β-allenyl side chain. β-Allenyl substituted-α-iodocycloalkanones were prepared from 2-cyclohexenones by 1,4-addition and trapped as silyl enol ethers, then added in the mixture of NaI and m-CPBA afforded the α-iodocycloalkanones as starting materials. We use aluminum chloride and iodonium source to induce the ionic iodo carbocyclization. Because of the difficulty of separation, we did many experiments in order to prove that whether we got cyclized products or not. We supposed it may be the structure factor caused the reason why we didn’t get the cyclized products but only the addition products were observered.

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