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分子印跡技術合成人工麝香及香豆素吸附劑及其基於磁性修飾的樣品前處理應用
Thesis

分子印跡技術合成人工麝香及香豆素吸附劑及其基於磁性修飾的樣品前處理應用

蔣昭歡
Masters, 國立清華大學, 奈米工程與微系統研究所
2013

Abstract

分子印跡高分子 合成麝香 香豆素 吸附劑 綠色 molecularly imprinted polymer synthesis musk coumarin adsorbent green
Artificial fragrances widely used in cosmetics, perfumes, detergents and other daily necessities are good alternatives to expensive natural flavors. Consequently, domestic sewage containing significant amount of artificial fragrances is discharged into the aquatic environment. Artificial fragrances are usually non-biodegradable, and results in bioaccumulation, disturbing the biological chain. Musk is very popular since ancient times. Deer musk is expensive and rare, therefore synthetic musk has gained more popularity. Musk-T, one of the synthetic musk, is used in my research. Another chemical is coumarin, which is also widely used as a fragrance in our daily life. But it is reported by the Health and Consumers Department of the European Union that coumarin is an allergen. In my research, MIPs for Musk-T and coumarin are successfully prepared, where MAA is used as the functional monomer, EGDMA as the cross-linker, and the polymerization reaction is initiated by AIBN. The average size of MIPs for Musk-T is 400-500 nm, and for the concentration of 0.05mM-1mM, the adsorption capacity is in between 1.88mg/g and 13.80mg/g. The highest imprinting factor is 4.1, and the lowest is 2.4. The size of MIPs for coumarin is 300-400 nm, the adsorption capacity is between 0.39-2.89 mg/g during the sample concentration of 0.02-0.5 mM. The imprinting factor is between 2.7 and 10.1, and has a good selectivity. The data is also analyzed by Scatchard Equation. Results show that there are two kinds of adsorption on the surface of both MIPs, specific binding and nonspecific binding. At last, the MIPs is modified by Fe3O4 using the EDC/NHS system, which makes the MIPs more convenient when it is used in the pretreatment process.

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