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合成及分析合適於熱療法之奈米顆粒
Thesis

合成及分析合適於熱療法之奈米顆粒

許書斌
Masters, 國立清華大學, 工程與系統科學系
2006

Abstract

奈米顆粒 氧化鐵 化學合成 高頻升溫 鐵硼
In this thesis, we synthesize and analyze the magnetic nanoparticles suitable for cancer therapy. Fe(acac)3, 1,2-hexadecanediol, and the surfactant were mixed in phenyl ether and heated to reflux to synthesize the iron oxide nanoparticles. We increase and control the particles size from 4 to 25 nm by changing the amount of the surfactant or adding the 4 nm seed particles in. And we change in process; we can synthesize the nanoparticles with two kinds of size. If part of the Fe(acac)3 is substituted by Mn(acac)2, it is iron/manganese oxide nanoparticle. The nanoparticles were analyzed by XRD, VSM, and X-ray absorption spectra and we demonstrated that the structure of the iron oxide is 60 % Fe3O4 and 40 % γ-Fe2O3. It is speculated that MnFe2O4 structure is appeared by adding the manganese precursor. The magnetic filed of the saturation magnetism increased by adding the manganese element. And the center of M-H loops of the iron/manganese nanoparticles would be shifted up to 50 Oe. We speculated that it is a core/shell structure judged from the Mn L-edge, O K-edge absorption spectra. Except the iron oxide nanoparticles, we also try to synthesize the iron boride nanoparticles. Though the iron boride nanoparticles could not be restricted to nanosize, the experimental results could be supplied for reference.

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