Abstract
Organic catalyst play an important role in asymmetric synthesis, the new catalyst and new synthetic method have continuted to be found until now. Scientists pay close attention to N-heterocyclic salt catalysed asymmetric reaction these years. The thesis is developed the triazolium salts 16、19 and thiazolium salts 22、25、28、31、35、36 as catalysts for intramolecular cross keto-aldehyde benzoin condensation . Keto-aldehyde 37 was selected as the starting material to studied intramolecular cross keto-aldehyde benzoin reation . After optimization solvents 、bases、temperature, the corresponding cross keto-aldehyde benzoin condensation product 38 was obtained in 35 % yield and 41 %ee .