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未受訓練之黑腹果蠅的短期空間記憶
Thesis

未受訓練之黑腹果蠅的短期空間記憶

顏宏修
Masters, 國立清華大學, 系統神經科學研究所
2015

Abstract

果蠅 短期記憶 LED 螢幕 行為實驗 Buridan's paradigm
Memory can be classified into long-term memory (LM) and short-term memory (SM). We are particularly interested in the mechanism of the SM between two of them. Owing to the quantity of neurons in human’s brain and the efficiency of computer, we chose Drosophila melanogaster (fruit fly) as studying model. We started with the research of how the fly’s SM affects its walking behavior and hoped that we can apply the result to the human’s brain in the future. In order to research fly’s behavior and to demonstrate detailed features in SM, we built our own LED arena based on recent designs. In Drosophila’s research, SM was demonstrated by Buidan’s paradigm. We created a protocol, which is based on Buidan’s paradigm to study the walking behavior of fruit fly. We also created a new method to analyze fly’s behavior and the effect of fly’s SM. Our result indicates that a fly’s walking behavior can be categorized into three basic types after the target was off set. Further result shows that one of the fly’s behaviors can be affected by its SM. During the analysis, we also observed the possible that the fly maybe have the ability of retaining SM for more than 60 seconds.

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